Celgene Corporation

Erythroid Maturation Needs to Stay on Track

Chronic anemia may result from an erythroid maturation defect1,2

Ineffective erythropoiesis may be characterized by a defect in erythroid maturation, which could lead to chronic anemia and burdensome complications for patients with some hematologic diseases.1-3

Research, however, is expanding what we know.

Stay on track, and receive periodic updates about anemia that may result from an erythroid maturation defect.

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References: 1. Liang R, Ghaffari S. Advances in understanding the mechanisms of erythropoiesis in homeostasis and disease. Br J Haematol. 2016;174(5):661-673.
2. Santini V. Anemia as the main manifestation of myelodysplastic syndromes. Semin Hematol. 2015;52(4):348-356. 3. Gupta R, Musallam K, Taher A,
Rivella S. Ineffective erythropoiesis: anemia and iron overload. Hematol Oncol Clin N Am. 2018;32(2):213–221.